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Dà Zǎo
大棗
| Pharmaceutical name |
Jujubae Fructus
jujube, Chinese date
“big date” |
| Category |
Tonify Qi |
| Key Properties |
Tonifies the Qi and Blood
Generates fluids
Harmonizes the Spleen
Moderates the toxic effects of other herbs |
| Properties |
Sweet
Warm |
| Tropism |
SP, ST |
| Actions & Indications |
1) Tonifies SP & Augments Qi
2) Nourishes Blood & Calms the Spirit
3) Moderates & Harmonizes Harsh Properties of other herbs |
| Dosages |
3-12 dates or 10-30g |
| Contraindications (TCM) |
Excess Heat, Damp-Heat, or Phlegm-Heat
Not recommended with intestinal parasites
Excessive use may cause tooth decay due to high sugar content |
| Contraindications (Western) |
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| Chemical Composition |
Betulinic acid, eanothic acid, oleanolic acid, crataegolic acid, alphitonic acid, zizyphus saponin I, II, III; jujuboside A, B; mashnic acid_ |
| Pharmacological Effects |
• Generalized: in one study, 36 mice were divided equally into treatment group and placebo group; treatment group received continuous administration of a 30% Da Zao decoction at 0.3 ml/kg; after three weeks, treatment group mice had a significant increase in body weight, muscle strength, and physical endurance when compared to placebo group; average weight gain was 3.0 grams in treatment group, and 1.6 grams in placebo group; duration of swimming time was 3 minutes and 50 seconds in treatment group, and 2 minutes and 30 seconds in placebo group
• Antineoplastic: several components have demonstrated inhibitory influence on cancer cells; continuous administration of mashnic acid for 14 days was more effective than 5- Fluorouracil in inhibiting growth of cancer cells
• Sedative: sedative effect on CNS; lowers blood pressure and reduces spontaneous motor activities
• Hepatoprotective: protective effect on liver; in one study, rabbits that received injections of Da Zao recovered much faster from carbon tetrachloride-induced liver damage than control group |
| Herb-Drug Interactions |
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| Classical Formula(s) |
Bai Zhu Fu Zi Tang (White Atractylodes and Aconite Accessory Root Decoction) 白朮附子湯 Di Huang Yin Zi (Rehmannia Drink) 地黃飲子 Fang Ji Huang Qi Tang (Stephania and Astragalus Decoction) 防己黃耆湯 Huang Lian Tang (Coptis Decoction) 黃蓮湯 Huang Long Tang (Yellow Dragon Decoction) 黃龍湯 Huang Qi Gui Zhi Wu Wu Tang (Astragalus and Cinnamon Twig Five-Substance Decoction) 黃芪桂枝五物湯 Huang Qin Tang (Scutellaria Decoction) 黃芩湯 Ju Pi Zhu Ru Tang (Tangerine Peel and Bamboo Shavings Decoction) 橘皮竹茹湯 Mai Men Dong Tang (Ophiopogonis Decoction) 麥門冬湯 Shi Pi Yin (Bolster the Spleen Decoction) 實脾飲 Shi Zao Tang (Ten-Jujube Decoction) 十棗湯 Ting Li Da Zao Xie Fei Tang (Lepidium and Jujube Decoction) 亭藶大棗瀉肺湯 Bai Zi Ren Wan (Arborvitae Seed Pill) 柏子仁丸 Ban Xia Bai Zhu Tian Ma Tang(Pinellia, White Atractylodes & Gastrodia Decoction) 半夏白朮天麻湯 Ban Xia Xie Xin Tang (Pinellia Decoction to Drain the Epigastrium) 半夏瀉心湯 Chai Ge Jie Ji Tang (Buplerum and Kudzu Decoction to Release the Muscle Layer) 柴葛解肌汤 Chai Hu Gui Zhi Tang (Bupleurum and Cinnamon Twig Decoction) 柴胡桂枝湯 Chai Hu Jia Long Gu Mu Li Tang (Bupleurum plus Dragon Bone and Oyster Shell Decoction) (delete qian dan) 柴胡加龍骨牡蠣湯 （減鉛丹） Da Chai Hu Tang (Major bupleurum decoction) 大柴胡湯 Da Qing Long Tang (Major Bluegreen Dragon Decoction) 大青龍湯 Dang Gui Si Ni Tang (Tangkuei Decoction for Frigid Extremities) 當歸四逆湯 Ge Gen Tang (Kudzu Decoction) 葛根湯 Gui Pi Tang (Restore the spleen decoction) 歸脾湯 (归脾汤) Gui Zhi Jia Long Gu Mu Li Tang (Cinnamon Twig Decoction plus Dragon Bone and Oyster Shell) 桂枝加龍骨牡蠣湯 Huo Xiang Zheng Qi San (Agastache powder to Rectify the Qi) 藿香正氣散 (藿香正气散) Jia Jian Wei Rui Tang (Modified Solomon's Seal Decoction) 加減葳蕤湯 Jiu Xian San (delete Mi Zhi Ying Su Ke) (Nine-Immortal Powder) 九仙散（減蜜製罌粟殼） Ping Wei San (Calm the Stomach Powder) 平胃散 Sheng Yang Yi Wei Tang (Raise the Yang and Augment the Stomach Decoction) 升陽益胃湯 Shi Quan Da Bu Tang (All-inclusive great tonifying decoction) 十全大補湯 (十全大补汤) Su Zi Jiang Qi Tang (Perilla Fruit Decoction for Directing Qi down) 蘇子降氣湯 (苏子降气汤) Wen Dan Tang (Warm Gallbladder Decoction) 溫膽湯 (温胆汤) Wu Zhu Yu Tang (Evodia Decoction) 吳茱萸湯 Xiao Chai Hu Tang (Minor Bupleurum Decoction) 小柴胡湯 (小柴胡汤) Xiao Jian Zhong Tang (Minor construct the middle decoction) 小建中湯 Xing Su San (Apricot Kernel and Perilla Leaf Powder) 杏蘇散 (杏苏散) Xuan Fu Dai Zhe Tang (Inula & Hematite Decoction) 旋覆代赭湯 Yu Ping Feng San (Jade windscreen powder) 玉屏風散 (玉屏风散) Zai Zao San (Renewal Powder) 再造散 Zhi Gan Cao Tang (Prepared licorice decoction) 炙甘草湯 (炙甘草汤) Zi Yin Jiang Huo Tang (Decoction to Enrich the Yin and Direct Fire Downward) 滋陰降火湯 Gui Zhi Tang (Cinnamon Twig Decoction) 桂枝湯 Ba Zhen Tang (Eight-Treasure decoction) 八珍湯
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This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.
