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Gé Gēn 葛根

Pharmaceutical name Puerariae Radix kudzu root
Category Cool, Acrid, Release the Exterior
Key Properties Raises clear Yang qi (Yang Ming)
Encourages ST qi
Release Heat (muscle) & vents rashes
Alleviates thirst by raising ST fluids, treats diarrhea
Properties Sweet
Acrid
Cool
Tropism SP, ST
Actions & Indications 1) Discharges Exterior Condition, releases Muscles (Headache, stiff upper back)
2) Relieves Heat & generate Fluids (wasting & thirsting, diabetes)
3) Vents (rashes) & Discharges Measles
4) Raises the Yang, Stops (any) Diarrhea (Excess or Deficiency)
5) Treats Symptoms of Hypertension
Dosages 9-21 g
Contraindications (TCM) Caution with Cold in ST, Yang Def, may cause nausea/vomiting
Caution during summer when excess perspiration accompanies Wind-Heat invasion
Contraindications (Western)
Chemical Composition Isoflavonoids 1.43 to 12.30% (puerarin, daidzin, daidzein, daidzein 4,7-diglucoside, formononetin, genistein), triterpenoid sapogenols
Pharmacological Effects • Cardiovascular: marked effectiveness in dilating coronary blood vessels, relieving spasms of these vessels, and reducing oxygen requirement of cardiac muscles; administration of water or alcohol extracts via intraperitoneal or subcutaneous injection effective in treating rats with acute myocardial ischemia; also dilates the blood vessels of the brain and increases local perfusion
• Antiplatelet: puerarin inhibits platelet aggregation in mice
• Antihypertensive: water and alcohol extracts have marked effectiveness in lowering blood pressure
• Antipyretic: mild antipyretic action through vessel dilation
• Antidiabetic: decoction has mild influence in lowering blood glucose levels
• Antispasmodic: relieves intestinal muscle spasms and cramps
• Antialcoholic: isoflavonoids, namely daidzin and daidzein, associated with marked antialcoholic effects in hamsters which consumed large amounts of ethanol
Herb-Drug Interactions • Antidiabetics: use with caution with insulin, sulfonylureas, and other antidiabetic medications as combination may have a synergistic effect, leading to hypoglycemia
• Anticoagulant or antiplatelet drugs: use with caution in patients who take anticoagulant or antiplatelet medications; may potentiate the effect of drugs such as warfarin
Classical Formula(s)


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This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.