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Huáng Yào Zǐ 黄藥子

Pharmaceutical name Dioscoreae bulbiferae Rhizoma dioscorea bulbifera tuber "yellow medicine seed"
Category Transform Phlegm Heat
Key Properties Toxic
Reduces scrofula
Cools the Blood
Alleviates Bleeding
Resolves Toxicity
Properties Bitter
Cold
Tropism LV, LU
Actions & Indications 1) Dissipates Nodules and Reduces Goiter
2) Clears Heat and Resolves Toxicity
3) Cools the Blood and Stops Bleeding
4) Stops Coughs and Calms Wheezing
Dosages 6-15g
Contraindications (TCM) CI: Toxic, overdosage must strictly be avoided. Not be administered to patients with a history of hepatic dysfunction; long-term use may cause vomiting, diarhea, abdominal pain and other gastrointestinal issues
Contraindications (Western)
Chemical Composition Disgenin, yamogenin, diosbulbins A, B, C, D; iodine
Pharmacological Effects • Effect on the thyroid gland: in rats with normal thyroid glands, oral administration did not affect body weight, basal metabolic rate, or weight of thyroid gland; in subjects with hypertrophy of thyroid gland caused by a small amount of potassium thiocyanate or by lack of iodine in diet, herb had marked therapeutic effect to reduce enlargement and increase content of serum protein-bound iodine
• Cardiovascular: water and alcohol preparations show inhibitory action on frog heart specimens
• Effects on smooth muscle: water and alcohol preparations inhibit smooth muscle of intestines in rabbits, but stimulate smooth muscle of uterus in rabbits and rats; alcohol preparation has faster onset of action and more potent effect
• Antibiotic: inhibitory action on various pathogenic fungi
Herb-Drug Interactions
Classical Formula(s)


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This information is a reference tool for Chinese herbal studies. It is not intended to replace professional medical advice. Please consult a primary health professional if you require health advisory.